active

Ascorbyl Glucoside

Evidence tier

MODERATE

Evidence score

HQ studies

Total studies

Goal scores

Acne

11 studies

Brightening

11 studies

Barrier

11 studies

Sensitivity

11 studies

Hydration

11 studies

Sebum

11 studies

Anti Aging

11 studies

Interactions

synergy · Tocopheryl Acetate

Stable vitamin C derivative + stable vitamin E derivative. Same antioxidant recycling mechanism as pure C+E but with improved stability.

antagonism · Benzoyl Peroxide

BP oxidizes vitamin C derivatives, reducing their antioxidant efficacy.

antagonism · Copper Gluconate

Copper ions catalyze oxidative degradation of vitamin C derivatives. Metal-antioxidant incompatibility.

Citations

PMID:40091954
Comparative Efficacy of Skin-Lightening Formulations in Suppressing Ultraviolet B (UVB)-Induced Arachidonic Acid, Alpha-Melanocyte-Stimulating Hormone (α-MSH), and Melanin Expression: An In Vitro Keratinocyte-Melanocyte Co-culture Study.
PMID:37607774
Transdermal Sustained Release Properties and Anti-Photoaging Efficacy of Liposome-Thermosensitive Hydrogel System.
PMID:40178310
In Vitro, Ex Vivo, Instrumental, and Clinical Assessment of a Novel Anti-aging Serum Targeting Oxidative Stress.
PMID:40317690
Efficacy in Clinical Studies of a Skin Care Serum Formula Containing 7 Short and Long Saccharides and Bacterial Fractions to Repair and Strengthen the Skin Barrier From Aggressions in Intense Conditions.
DOI:10.1159/000139128
Permeation and Metabolism of a Novel Ascorbic Acid Derivative, Disodium Isostearyl 2-O-<i>L</i>-Ascorbyl Phosphate, in Human Living Skin Equivalent Models
PMID:41640789
Clinical Age-reversal Quantification of a Facial Skincare Regimen with Sirtuin-targeting Ingredients in a Multiethnic Population.
PMID:40515408
Hydrogel-Based Therapies for Photoaging: Current Advances and Future Perspectives.