active

Phytosphingosine

Evidence tier

MODERATE

Evidence score

HQ studies

Total studies

Goal scores

Acne

2 studies

Brightening

2 studies

Barrier

2 studies

Anti Aging

2 studies

Hydration

2 studies

Sebum

2 studies

Sensitivity

2 studies

Interactions

synergy · Ceramide NP

Phytosphingosine is a ceramide precursor that enhances ceramide synthesis in the stratum corneum. Together they strengthen the lipid barrier.

Citations

PMID:40408261
Topical supplementation with physiological lipids rebalances the stratum corneum ceramide profile and strengthens skin barrier function in adults predisposed to atopic dermatitis.
PMID:40635529
A Randomized, Investigator-Blinded, Split-Face, Controlled Trial Evaluating the Efficacy and Satisfaction of a Topical Product Containing Blueberry Extract and Pro-Xylane Combined With Micro-Focused Ultrasound for Anti-aging.

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