active

Mandelic Acid

Evidence tier

LOW

Evidence score

HQ studies

Total studies

Goal scores

Acne

5 studies

Brightening

5 studies

Barrier

5 studies

Anti Aging

5 studies

Hydration

5 studies

Sebum

5 studies

Sensitivity

5 studies

Interactions

synergy · Salicylic Acid

Mandelic acid (AHA) addresses surface texture while salicylic acid (BHA) penetrates pores. AHA+BHA combination for oily, textured skin.

antagonism · Retinol

AHA + retinoid can cause excessive exfoliation and irritation. Better alternated on different nights.

Citations

DOI:10.1055/s-0038-1676048
Effects of Topical Mandelic Acid Treatment on Facial Skin Viscoelasticity
DOI:10.1159/000486461
Clinical and Videodermoscopic Evaluation of the Efficacy, Safety, and Tolerability of a Shampoo Containing Ichthyol, Zanthalene, Mandelic Acid, and Honey in the Treatment of Scalp Psoriasis
DOI:10.1111/srt.70222
Enhanced Skin Permeation and Pigmentation Reduction Effects of a Novel Tranexamic Acid‐Mandelic Acid Ion‐Pairing Complex
PMID:41715896
The Effect of Microneedling Mesotherapy, Chemical Exfoliation and Combination Therapy on Selected Skin Parameters and Cutibacterium acnes Colonization in Women With Oily Skin.
DOI:10.47607/ijresm.2020.334
Glycolic Acid, Lactic Acid, Mandelic Acid, Salicylic Acid, Citric Acid, Gluconolactone: Skin Exfoliators in Combination Therapy of Acne Vulgaris

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