active

Aloe Vera

Evidence tier

VERY_LOW

Evidence score

HQ studies

Total studies

Goal scores

Barrier

9 studies

Sebum

9 studies

Brightening

9 studies

Acne

9 studies

Sensitivity

9 studies

Anti Aging

9 studies

Hydration

9 studies

Interactions

synergy · Panthenol

Both soothe irritated skin through different mechanisms. Aloe provides cooling hydration while panthenol supports tissue repair.

myth · Retinol

Myth: "aloe vera deactivates retinol." No evidence. Aloe gel is pH-neutral and may actually soothe retinol irritation.

Citations

PMID:17026654
Moisturizing effect of cosmetic formulations containing <i>Aloe vera</i> extract in different concentrations assessed by skin bioengineering techniques
PMID:36249738
Aloe vera for prevention of radiation-induced dermatitis: A systematic review and cumulative analysis of randomized controlled trials.
SRC:7a3a22bb-3c1e-47ff-adbc-c3c5f9b3b5a4
FORMULATION AND CHARACTERIZATION OF ALOE VERA COSMETIC HERBAL HYDROGEL
PMID:39566518
Aloe vera and the Proliferative Phase of Cutaneous Wound Healing: Status Quo Report on Active Principles, Mechanisms, and Applications.
SRC:a6b35895-351a-4aaa-a45a-456d7f4c6e78
FORMULATION AND CHARACTERIZATION OF ALOE VERA COSMETIC HERBAL HYDROGEL
PMID:36264753
Second-Degree Burns and Aloe Vera: A Meta-analysis and Systematic Review.
DOI:10.1159/000265682
Pre-Treatment with Aloe vera Juice Does Not Enhance the in vitro Permeation of Ketoprofen across Skin
PMID:40807366